DEAR READERS: Take a look at the alarming title of this recently published scientific report: “Glyphosate presence in human sperm: First report and positive correlation with oxidative stress in an infertile French population.”
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The report, by Claudine Vasseur and associates, was published this month in the journal Ecotoxicology and Environmental Safety. It concerns the widely used herbicide Roundup, which Bayer took over from Monsanto in 2018. Roundup’s main ingredient, glyphosate, may well be involved in the fertility decline in the U.S. and other countries where in vitro fertilization is in rising demand.
This harmful herbicide is widely used on many human and animal feed crops. It is also sprayed on wheat and other grains at harvest so the plants die and dry faster. It is used by municipalities, corporations and homeowners to kill “weeds” on their properties.
The adverse effects of glyphosate on the reproduction of rats, mice and other animals have been documented and ignored for years. For instance, see the 2017 study “Effects of glyphosate exposure on sperm concentration in rodents: A systematic review and meta-analysis” by Wenyan Cai and associates (Environmental Toxicology and Pharmacology) and the 2018 study “The Effect of Glyphosate on Human Sperm Motility and Sperm DNA Fragmentation” by George Anifandis and associates (International Journal of Environmental Research and Public Health).
The potential negative effects on human reproduction systems merely add to the long list of reasons not to use these chemicals. Herbicide residues in many pet foods can disrupt the healthy gut microbiome and lead to irritable and inflammatory bowel conditions, interfere with digestion and trigger allergic reactions when the so-called leaky gut syndrome develops. And lawsuits by users of glyphosate who got cancer (non-Hodgkin’s lymphoma) have pushed Bayer to take steps to avoid bankruptcy and further liability.
In my opinion, the harmful effects of glyphosate and other herbicides on our health, wildlife (especially aquatic life) and ecosystems -- marine, freshwater and terrestrial alike -- amount to crimes against humanity and nature.
DEAR DR. FOX: I have a 6-year-old, 11-pound shih tzu. About three years ago, she became terrified of thunder and fireworks.
When she hears those noises, her eyeballs look like saucers, she hyperventilates with her tongue hanging out, and she runs around the house looking everywhere for the noises. Nothing calms her down. If I am in bed, she tries to jump up. Once up, she immediately jumps off, runs around and tries to jump up again. Even once the noises stop, she continues hyperventilating, sometimes for a couple of hours afterwards.
I have tried holding her, which does not work for very long, and she scratches to get down. I have tried to drown out the noises by blasting the television, to no avail. I have tried to play soothing music -- again, no luck.
One vet recommended trying a ThunderShirt -- did not work. Since my dog is not fond of being held when she hears these noises, she tried desperately to rip it off.
After that, vets have recommended giving her 25 mg of trazodone one hour prior to any expected stressful events. It does not seem to do much, other than perhaps calming her down a little quicker afterwards. Also, it is hard to always anticipate when these things will occur.
Twice this past summer, I was out walking with her in the evening (after dark), when suddenly there were thunderclaps in the distance. Both times, she pulled me back to the house as hard as she could. Ever since, she refuses to go out in the dark, clearly associating it with the noise. Now I must get her out before dark for her last walk of the day.
Thunder and fireworks seem to be the only noises that trigger her. Other sounds like lawn mowers, leaf blowers, trucks and sirens have no effect.
Do you have any suggestions as to how I can better calm her? I'll even try a different medication, if necessary. I am even worried she may one day have a heart attack from this stress. -- D.L., Wellington, Florida
DEAR D.L.: As my dog Kota became older, she developed some agitation when a thunderstorm was coming. I simply turn up the TV and close the curtains -- but as you know, this doesn't work for every dog. You have done everything to help your poor dog cope with her phobia, which could indeed have dire consequences if left unchecked.
The widely prescribed trazodone can make some dogs even more anxious and accelerate their heart rate. A dose of melatonin (3 mg to 6 mg) about half an hour before a storm or fireworks may help, along with having the curtains drawn and the TV or music up loud.
Some dogs, like some of us, also respond to sudden changes in barometric pressure associated with a storm front, setting up a conditioned anxiety reaction. For this and for the noise-related stress, I would ask your veterinarian to prescribe a course of treatment with alprazolam (Xanax) or clomipramine. These can be very effective in reducing dogs’ anxiety and can certainly help desensitize your dog to going outdoors as darkness falls.
(Send all mail to animaldocfox@gmail.com or to Dr. Michael Fox in care of Andrews McMeel Syndication, 1130 Walnut St., Kansas City, MO 64106. The volume of mail received prohibits personal replies, but questions and comments of general interest will be discussed in future columns.
Visit Dr. Fox’s website at DrFoxOneHealth.com.)