DEAR DR. BLONZ: There is a history of macular degeneration in my family, and I understand that lutein and zeaxanthin are nutrients needed to slow its progression. What is your view on supplements as a preventive? My father and both of his siblings were diagnosed with this condition by age 75. -- M.F., Charlotte, North Carolina
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DEAR M.F.: The macula is the part of the eye where the images are focused. At the center of the macula is the "fovea centralis," the point of the eye where our vision is at its best. It is the macula where the electrical impulses that correspond to what we are looking at are initiated. Milliseconds later, after the signals have made their way to the brain via the optic nerve and have been interpreted, we understand what we are seeing.
An unfortunate condition associated with aging is a breakdown of these tissues. Macular degeneration is the leading cause of blindness in older Americans. The precise cause of macular degeneration is not yet known, but the retina -- and the lens -- are thought to be susceptible to oxidative damage.
Antioxidants, including zinc, vitamins C, E and A and selenium, all have reactions that prevent unwanted oxidation. However, the key is to have antioxidants that distribute to all vulnerable tissues, which points to the need to maintain a diet that includes a variety of healthful, whole foods that provide a range of compounds to protect all tissues.
The carotenoids, particularly the antioxidant compounds lutein and zeaxanthin, are known to concentrate in the macula. In fact, they are the only carotenoids known to be in the retina's macular region, and are referred to as macular pigments.
Spinach and corn are good sources of lutein and zeaxanthin. A study in the journal Investigative Ophthalmology and Visual Science from August 1997 reported how increased intake of these foods effectively increased blood levels of the key macular pigment compounds. A study in the same journal in October 2000 reported increased macular pigment levels after 12 weeks of supplemental lutein, or 10 mg per day. In the June 2000 issue of the American Journal of Clinical Nutrition, another study reported how servings of corn and spinach effectively raised blood levels of these macular pigments.
Other good food sources of lutein and zeaxanthin include kale, collard greens, cress leaf, Swiss chard, chicory leaf, mustard greens, beet greens, red pepper, okra, endive, celery, romaine lettuce, leek, broccoli, leaf lettuce, green peas, pumpkin, iceberg lettuce, Brussels sprouts, yellow pepper and green beans. Fruits contain lesser amounts, but some of the best include avocado, plums, kiwis, pears and grapes.
Supplements are a reasonable option, but they do not replace the need to eat healthful foods. When taken as a supplement, lutein is best absorbed when taken with meals that contain fat. Be aware that while many multipurpose supplements claim to contain lutein (or zeaxanthin), the amounts can vary. Always check the label and compare it with the 10 mg per day used in the study cited above.
Read more about macular degeneration at b.link/xu9pj8j, which includes a section on treatments and therapies.
Send questions to: "On Nutrition," Ed Blonz, c/o Andrews McMeel Syndication, 1130 Walnut St., Kansas City, MO 64106. Send email inquiries to questions@blonz.com. Due to the volume of mail, personal replies cannot be provided.